Osteitis fibrosa describes the bone changes seen in renal osteodystrophy secondary to longstanding hyperparathyroidism. A case of leontiasis ossea which was primarily investigated as a result of oral findings is presented. Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. Leontiasis ossea the british journal of radiology vol 6. Leontiasis ossea is not itself a disease, but a condition of other diseases such as paget. Radiological diagnostic features of uremic leontiasis ossea. The term leontiasis ossea is widely applied and can be employed by the rule of good usage. Leontiasis ossea the british journal of radiology vol 19. This study presents a report on a patient with advanced hyperparathyroidism with skeletal changes compatible with leontiasis ossea.
Leontiasis definition of leontiasis by medical dictionary. These findings are characteristic of uremic leontiasis ossea. Leontiasis ossea is a rare medical condition, with characteristic overgrowth of the facial and cranial bones. In leontiasis ossea the cranial and facial bones are more or less markedly thickened, depending upon the stage of the disease. Leontiasis ossea is a rare presentation of renal osteodystrophy with few reports in literature. Pdf leontiasis ossea a paleopathologic case report. Paget disease of the bone presenting as leontiasis ossea, carvalho ruben, pereira ina a. Excerpt hyperostosis cranii, craniosclerosis, or leontiasis ossea is a rare disease found most often in. The development of a bone is a complicated process. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a broader meaning encompassing other lesions that have similar appearance 1,4 the distinction is made between true leontiasis ossea craniofacial. Dec 25, 2012 leontiasis ossea, a rare disease characterized by an overgrowth of the facial and cranial bones. The keyword leontiasis ossea has no diagnostic significance. Leontiasis ossea and post traumatic cervical cord contusion. We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail.
Ivimey, of new york, described a case in a boy of jewish parentage, aged 11, on which there was bone distrophy with characteristics of leontiasis ossea, shading to osteitis deformans as far as the skull was concene, and at the same time an apparent transition in the long bones to osteitis fibrosa cystica with thinning and threatening fracture. Leontiasis ossea, also known as leontiasis or lion face, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a br. A long bone arises from a solid mass of mesenchyme which turns into a strong but delicate and light tubular structure, constantly adapting its architecture to the needs of bodily growth and stresses and strains. Thank you for your interest in spreading the word about the bmj. The term leontiasis ossea is reported to be first coined in 1864 by the famed virchow 1. Leontiasis ossea, a rare disease characterized by an overgrowth of the facial and cranial bones.
If, however, the facial deformity is the result of change in the underlying bone, the slightly restricted term of leontiasis ossea is applicable. They give the impression of being swollen, but the resemblance to normal bone remains. A case of leontiasis ossea, megalocephalie, or hyperostosis. Files are available under licenses specified on their description page. The common form is that in which one or other maxilla is affected, its size progressively increasing both regularly and irregularly, and thus encroaching on the cavities of the orbit, the mouth, the nose and its accessory sinuses. Leontiasis ossea is also known as lion face syndrome due to affected patients face resembling that of a lion, and it can be caused by pagets disease, fibrous dysplasia, gigantism, tumors of. He dwelt at length on this localization of bone hypertrophy because it served him well in the. Leontiasis ossea is a rare medical condition which is characterized by an overgrowth of the facial and cranial bones secondary to chronic renal failure and secondary hyperparathyroidism. We report a 19yearold man with longstanding chronic renal failure with a severe form of osteitis fibrosa affecting the jaws and other maxillofacial bones causing bizarre facial and dental deformity in a patienturaemic leontiasis ossea. May 02, 2006 these findings are characteristic of uremic leontiasis ossea. Paget disease of the bone presenting as leontiasis ossea, carvalho ruben, pereira ina.
Jun 01, 2015 leontiasis ossea, also known as leontiasis or lion face, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. Apr 22, 2004 osteitis fibrosa describes the bone changes seen in renal osteodystrophy secondary to longstanding hyperparathyroidism. Its most severe osseous complication is characterized by massive thickening of the cranial vault and facial bones, called uremic leontiasis ossea ulo, with only few cases reported in the literature. Osteitis fibrosa is a term that has been used for many years to designate any of a heterogeneous group of lesions of bone and is objectionable because it thus lacks any specific connotation. In one of his classic lectures delivered during the winter semester 18621863 at the university of berlin, virchow1 directed special attention to the hyperostoses affecting the facial and cranial bones. Pdf plus abstract uremic leontiasis ossea ulo, which occurs in the craniomaxillofacial region, is a sign of terminal stage osteitis fibrosa cystica or brown tumors and primarily caused by secondary hyperparathyroidism induced by renal failure. All structured data from the file and property namespaces is available under the creative commons cc0 license. Renal osteodystrophy is a common complication of endstage renal failure patients. Leontiasis ossea leonine facies or cervical canal stenosis are rare complications of polyostotic fibrous dysplasia pfd. Leontiasis ossea, also found in the literature as leontiasis or lion face, is a rare medical condition with characteristic overgrowth of the facial and cranial bones. Paget disease of the bone presenting as leontiasis ossea. Leontiasis ossea is believed to be the rarest and manifests clinically as widening of the interdental spaces, flattening of the nares and nasal bridge, and jaw enlargement. V s lee, m s webb, jr, s martinez, c p mckay, g s leight, jr. It is only a description of a symptom of bone disease with a broad variability such as pagets disease, fibrous dysplasia, hyperparathyroidism and condensing osteopathies.
Uremic leontiasis ossea find, read and cite all the research you need on researchgate. From the department of roentgenology and pathology, western reserve university and city hospital, cleveland, ohio. Leontiasis ossea is largely a historical term used to describe a number of conditions that result in the affected patients face resembling that of a lion. It is not a disease in itself, but a symptom of other diseases, including pagets disease, fibrous dysplasia, hyperparathyroidism and. Uremic leontiasis ossea, a rare presentation of severe renal. Aug 15, 2006 leontiasis ossea leonine facies or cervical canal stenosis are rare complications of polyostotic fibrous dysplasia pfd.
It is important to recognize features of uremic leontiasis ossea, as it may result in lifethreatening upper airway obstruction and compressive cranial neuropathy. If, however, the facial deformity is the result of change in the underlying bone, the slightly restricted term of. Leontiasis ossea is a term that can be used to describe the progressive hypertrophy of facial and cranial bones associated with a group of diseases, including paget disease and fibrous dysplasia. Get a printable copy pdf file of the complete article 457k, or click on a page image below to browse page by page. Although lion face is most frequently associated with craniofacial fibrous dysplasia, this condition can also be caused by pagets disease, fibrous.
It is not a disease in itself, but a symptom of other diseases, including pagets disease, fibrous dysplasia, hyperparathyroidism and renal osteodystrophy. Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical. Fatal uremic leontiasis ossea in longlasting uncontrolled. He dwelt at length on this localization of bone hypertrophy because it. Parenteral vitamin d was commenced for the patient, and she is awaiting parathyroidectomy. A case of leontiasis ossea, megalocephalie, or hyperostosis cranii. Uremic leontiasis ossea is a rare manifestation of renal osteodystrophy clinically characterized by jaw enlargement, widening of the nares, flattening of the nasal bridge, and increased interdental spacing.
Jun 24, 2019 pdf plus abstract uremic leontiasis ossea ulo, which occurs in the craniomaxillofacial region, is a sign of terminal stage osteitis fibrosa cystica or brown tumors and primarily caused by secondary hyperparathyroidism induced by renal failure. Several radiologic patterns of maxillofacial involvement have been described in the setting of renal osteodystrophy. A clinical and roentgenological entity report of a case j. Unlimited viewing of the article pdf and any associated supplements and figures. Pdf on jun 1, 2006, s kumar and others published bighead disease. View or download all content the institution has subscribed to. Article pdf available in italian journal of orthopaedics and traumatology 52. This case report documents dramatic leontiasis ossea in pfd as well as post traumatic cervical cord contusion due to hyperextension. Full text full text is available as a scanned copy of the original print version. There are present atypical features which leave the diagnosis between the pathologic entity described as leontiasis ossea and the clinical appearance known as leontiasis ossea the latter of which may be due to a number of underlying causes. Leontiasis ossea is a rare medical condition which is characterized by an overgrowth of the facial and cranial bones secondary to chronic renal. This case report documents dramatic leontiasis ossea in pfd as well as post traumatic cervical cord contusion due to hyperextension injury in a patient with generalized pfd involving the craniofacial bones, axial skeleton and entire spine with secondary cervical canal.
It causes severe skeletal deformity in the cranial bones. Leontiasis ossea in a patient with hyperparathyroidism. Leontiasis ossea definition of leontiasis ossea by medical. Leontiasis ossea, or lion face, is a historical term with no clinical significance used to characterize an overgrowth of the facial and cranial bones that can be caused by several diseases.
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